HMM Summary Page: TIGR00038

Functiontranslation elongation factor P
Gene Symbolefp
Trusted Cutoff185.80
Domain Trusted Cutoff185.80
Noise Cutoff136.65
Domain Noise Cutoff136.65
Isology Typeequivalog
HMM Length184
Mainrole CategoryProtein synthesis
Subrole CategoryTranslation factors
Gene Ontology TermGO:0003746: translation elongation factor activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006414: translational elongation biological_process
AuthorHaft DH, Richardson DL
Entry DateApr 20 1999 2:07PM
Last ModifiedFeb 14 2011 3:27PM
Commentfunction: involved in peptide bond synthesis. stimulate efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (by similarity). The trusted cutoff of this model is set high enough to exclude members of TIGR02178, an EFP-like protein of certain Gammaproteobacteria.
ReferencesDR PROSITE; PDOC00981; SE TIGR GA hmmls DR HAMAP; MF_00141; 485 of 498
Genome PropertyGenProp0741: translation elongation, bacterial (HMM)
GenProp0800: bacterial core gene set, 1 or more per genome (HMM)