HMM Summary Page: TIGR00037

Functiontranslation elongation factor IF5A
Gene Symboleif5A
Trusted Cutoff75.45
Domain Trusted Cutoff75.45
Noise Cutoff69.80
Domain Noise Cutoff69.80
Isology Typeequivalog
HMM Length130
Mainrole CategoryProtein synthesis
Subrole CategoryTranslation factors
Gene Ontology TermGO:0003743: translation initiation factor activity molecular_function
GO:0006413: translational initiation biological_process
AuthorRichardson DL, Haft DH
Entry DateApr 20 1999 2:07PM
Last ModifiedDec 7 2011 4:48PM
CommentRecent work (2009) changed the view of eIF5A in eukaryotes and aIF5A in archaea, hypusine-containing proteins, from translation initiation factor to translation elongation factor.
ReferencesRN [1] RM PMID:19424157 RT Hypusine-containing protein eIF5A promotes translation elongation. RA Saini P, Eyler DE, Green R, Dever TE RL Nature. 2009 May 7;459(7243):118-21. DR PROSITE; PDOC00274; DR HAMAP; MF_00085; 44 of 44
Genome PropertyGenProp0831: archaeal core gene set, exactly 1 per genome (HMM)