HMM Summary Page: TIGR00028
Accession | TIGR00028 |
Name | Mtu_PIN_fam |
Function | toxin-antitoxin system PIN domain toxin |
Trusted Cutoff | 73.60 |
Domain Trusted Cutoff | 73.60 |
Noise Cutoff | 73.45 |
Domain Noise Cutoff | 73.45 |
Isology Type | subfamily |
HMM Length | 143 |
Author | Haft DH |
Entry Date | Apr 20 1999 2:04PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein consist almost entirely of a PIN (PilT N terminus) domain (see Pfam PF01850). This family was originally defined a set of twelve closely related paralogs found in Mycobacterium tuberculosis, but additional members are found now Synechococcus sp. WH8102, etc. Inspection of genomic regions suggests these represent toxin components of toxin-antitoxin regions, potentially important to creating dormant persister cells. |
References | DR PFAM; PF01850; PIN domain |