| Accession | TIGR00023 |
| Name | TIGR00023 |
| Function | acyl-phosphate glycerol 3-phosphate acyltransferase |
| Gene Symbol | plsY |
| Trusted Cutoff | 137.20 |
| Domain Trusted Cutoff | 137.20 |
| Noise Cutoff | 62.40 |
| Domain Noise Cutoff | 62.40 |
| Isology Type | equivalog |
| EC Number | 2.3.1.- |
| HMM Length | 196 |
| Mainrole Category | Fatty acid and phospholipid metabolism |
| Subrole Category | Biosynthesis |
| Gene Ontology Term | GO:0005886: plasma membrane cellular_component |
| | GO:0006654: phosphatidic acid biosynthetic process biological_process |
| | GO:0008374: O-acyltransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents the full length of acylphosphate:glycerol 3-phosphate acyltransferase, and integral membrane protein about 200 amino acids in length, called PlsY in Streptococcus pneumoniae, YneS in Bacillus subtilis, and YgiH in E. coli. It is found in a single copy in a large number of bacteria, including the Mycoplasmas but not Mycobacteria or spirochetes, for example. Its partner is PlsX (see TIGR00182), and the pair can replace PlsB for synthesizing 1-acylglycerol-3-phosphate. |
| References | RN [1]
RM PMID:17308305
RT Topology and active site of PlsY: the bacterial acylphosphate:glycerol-3-phosphate acyltransferase.
RA Lu YJ, Zhang F, Grimes KD, Lee RE, Rock CO
RL J Biol Chem. 2007 Apr 13;282(15):11339-46. Epub 2007 Feb 16.
RN [2]
RM PMID:17645809
RT Involvement of the YneS/YgiH and PlsX proteins in phospholipid biosynthesis in both Bacillus subtilis and Escherichia coli.
RA Yoshimura M, Oshima T, Ogasawara N
RL BMC Microbiol. 2007 Jul 24;7:69.
DR InterPro; IPR003811; DUF205
DR PFAM; PF02660; DUF205
SE TIGR
AL clustalw
DR HAMAP; MF_01043; 351 of 377 |
| Genome Property | GenProp0837: 1-acylglycerol-3-phosphate biosynthesis, PlsX/Y pathway (HMM) |
