| Accession | TIGR00020 |
| Name | prfB |
| Function | peptide chain release factor 2 |
| Gene Symbol | prfB |
| Trusted Cutoff | 383.15 |
| Domain Trusted Cutoff | 383.15 |
| Noise Cutoff | 337.40 |
| Domain Noise Cutoff | 337.40 |
| Isology Type | equivalog |
| HMM Length | 365 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Translation factors |
| Gene Ontology Term | GO:0003747: translation release factor activity molecular_function |
| | GO:0006415: translational termination biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a PFAM HMM called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. |
| References | SE TIGR
GA hmmsw
DR HAMAP; MF_00094; 133 of 135 |
| Genome Property | GenProp0746: translation termination, bacterial (HMM) |
