HMM Summary Page: TIGR00006
| Accession | TIGR00006 |
| Name | TIGR00006 |
| Function | 16S rRNA (cytosine(1402)-N(4))-methyltransferase |
| Gene Symbol | rsmH |
| Trusted Cutoff | 154.30 |
| Domain Trusted Cutoff | 154.30 |
| Noise Cutoff | 114.95 |
| Domain Noise Cutoff | 114.95 |
| Isology Type | equivalog |
| EC Number | 2.1.1.199 |
| HMM Length | 310 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0008168: methyltransferase activity molecular_function |
| GO:0009252: peptidoglycan biosynthetic process biological_process | |
| Author | Richardson DL, Haft DH |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Aug 12 2012 7:26PM |
| Comment | This HMM describes RsmH, a 16S rRNA methyltransferase. Previously, this gene was designated MraW, known to be essential in E. coli and widely conserved in bacteria. |
| References | RN [1] RM PMID:22561317 RT Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA. RA Wei Y, Zhang H, Gao ZQ, Wang WJ, Shtykova EV, Xu JH, Liu QS, Dong YH RL J Struct Biol. 2012 Jul;179(1):29-40. Epub 2012 Apr 27. RN [2] RM PMID:10572301 RT mraW, an essential gene at the dcw cluster of Escherichia coli codes for a cytoplasmic protein with methyltransferase activity. RA Carrion M, Gomez MJ, Merchante-Schubert R, Dongarra S, Ayala JA RL Biochimie. 1999 Aug-Sep;81(8-9):879-88. RN [2] RM PMID:4563986 RT Cell wall peptidoglycan mutants of Escherichia coli K-12: existence of two clusters of genes, mra and mrb, for cell wall peptidoglycan biosynthesis. RA Miyakawa T, Matsuzawa H, Matsuhashi M, Sugino Y RL J Bacteriol. 1972 Nov;112(2):950-8. DR HAMAP; MF_01007; 272 of 272 |
| Genome Property | GenProp1082: 16S rRNA C1402 m(4)Cm modification (HMM) |
| GenProp0802: ribosome biogenesis proteins, bacteria (HMM) |